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10.3390/ijms252111469 282 ZielinskiM

Available from: Pokhrel B, Bhusal K

213 In CSCs, Notch overactivation has been linked to sustained cell proliferation, the inhibition of differentiation, and the upregulation of prosurvival genes

In addition, in rat endplate chondrocytes, the intervention of IGF-1 up-regulated the expression of MMP-13 through the ERK pathway, thereby inhibiting the decomposition of cartilage [30]