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After the lockdown measure was lifted, 3.7% (18/487) of responders were found to develop HCC, 4.1% (20/487) had an abnormal liver function test, 5.1% (25/487) had a HBV-DNA rebound and 9.2% (45/487) have not performed any outpatient review so far

Oncotarget 8 , 9951499530 (2017)

doi: 10.1155/2022/7993579 118 AliAAliSAqilMImamSSAhadAQadirA

Dalle-Donne, I., Giustarini, D., Colombo, R., Rossi, R

In vitro testing in an HBV cell-based model confirmed retention of IDR activity against tested variants, suggesting that these SNPs have no apparent influence on HBsAg declines in subjects treated with IDR

In this study, the entropy term was neglected due to its excessive computational cost and comparatively low prediction accuracy to the final binding free energy 56,57