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Its anti-inflammatory effects are mediated by its ability to suppress the expression and release of pro-inflammatory cytokines, such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-), in various cell culture models

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Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

While they act via identical mechanisms, AOD9604 is often preferred in oral administration studies due to its resistance to digestive enzymes, whereas standard 176-191 requires parenteral administration in research settings

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