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supporting the survival of exogenous cells and remaining NPCs in the intervertebral disc

Quantification of mitochondrial superoxide was similarly executed except that the samples were stained with 5 M MitoSox TM Red (Thermo Fisher Scientific)

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Population studies have indicated polymorphisms in genes such as COL1A1 , COL9A2 , COL11A1 , Aggrecan, and IL-1 may play a role in disc degeneration (Annunen et al., 1999