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N.WaiteT

10.1016/j.bbalip.2016.09.002 155 NewmanA

carried out the first clinical trial in humans with substantial benefits on quality of life and functional status after the administration of melatonin during chemo- and radiotherapy [66]

Mechanistically, erucic acid orchestrates this inhibition by impeding STAT3 phosphorylation and promoting ferroptosis

The gut microbial flora plays an important role in the CRC microenvironment

Cancer cells often exhibit elevated iron requirements to sustain proliferation, while tumor-initiating cancer stem cells (CSCs) display an even greater dependency, reflected by increased ferritin expression and iron uptake