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If consistently greater than 1000 then high CBS activity is likely Elevated ammonia and/or sulfate levels on an Organic Acids Test (OAT) Elevated B6 on an OAT test B6 may also be elevated during CBS up-regulations High Taurine Values Taurine is synthesized via Cysteine Elevated Orotate, Citrate and Isocitrate on an OAT test indicates elevated ammonia I take authorship for identifying two observations on a standard blood test that I have witnessed correlate with CBS pathway up-regulations: BUN (blood, urea, nitrogen) greater than 20 This is a crude indicator, and BUN may be elevated for other reasons, such as dehydration or renal dysfunction

Umeh ON, Beekman R, Dsa H, Friedman BJ

doi: 10.1111/j.1399-3054.2006.00632.x 15 BruemmerJ

A 3 s video of each mouse walking continuously, with no stopping or starting, was captured

Waist measurements drop noticeably