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Nanoparticles can be engineered to cross the BBB via receptor-mediated transcytosis or adsorptive-mediated transcytosis, or to bypass the BBB altogether through alternative routes such as intranasal delivery, as described in-depth in Section 4.3

Bailey etal

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The SWA power of each NREM sleep cycle obtained was normalized by the average power value of all NREM sleep cycles, and from these data, the SWA power of the first NREM sleep cycle was used as the indicator of sleep homeostasis for each participant

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The treatment is administered through direct injection into muscle tissue, typically in the upper arm, thigh, hip, or buttocks area [5]