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Moreover, the magnitude of this effect significantly depended on the dosage: median time to death, or ventilation support, was 570 days for placebo, 1,087 days for 25 mg, and 1,197 days for 50 mg methylcobalamin groups

C.XiaoC.et al (2022)

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This is because elevated homocysteine levels can be a marker for various conditions including heart disease, depression, cognitive disorders, and risk of fracture

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