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Immunology 7, 159

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Additionally, we estimated an ongoing annual burden of 46 hours per hospital with a cost of $3,610.88 per hospital, resulting in a total national burden of 276,092 hours (46 hours 6,002 hospitals) and total cost of $21,672,502 ($3,610.88 6,002 hospitals), to make required annual updates to the hospitals' standard charge information

[20] [7] This conversion is illustrated by the reduction of peroxides (via the sulfenate as an intermediate): GSH + R 2 O 2 GSOR + ROH GSOR + GSH GSSG + ROH Net reaction: 2 GSH + R 2 O 2 GSSG + 2 ROH (R = H, alkyl) and with free radicals, forming glutathionyl radicals (GS ) that may dimerize to disulfide: GSH + R RH + GS 1/2 GSSG Thiyl radicals (such as glutathionyl radicals) are themselves oxidizing species in biology, with a single-electron reduction potential sufficient for oxidation of nucleic acids, proteins and polyunsaturated lipids