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Sterling, criticizing the homeostatic vision, which in our opinion was Walter Cannons and not Hans Selyes ([39], in 1976, thus well before the emergence of the concept of allostasis, proposed the concept of heterostasis (from the Greek heteros or other) which documents his dynamic view of homeostasis

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These metabolic abnormalities not only interfere with the proliferation, differentiation, and maturation of spermatogonia but also further affect sperm quality and quantity through epigenetic modifications, oxidative stress, and apoptosis [37, 101, 160, 238]

Tang, J., Zhuo, Y

The interaction of carotenoids with Nrf2 enhances its translocation into the nucleus, which in turn activates glutathione S-transferases, an important family of detoxification enzymes that suppresses the level of oxidative stress