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doi: 10.1002/jsfa.12472 11

ISBN 978-1-84127-199-6

[1] The more advanced regulatory activity belongs to the combination product CagriSema (cagrilintide plus semaglutide), which reached Phase 3 and for which a New Drug Application was reported to have been filed with the FDA in late 2025

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Presymptomatic and symptomatic D-CAA showed increasing MRI abnormalities and decreasing vascular reactivity with age Conclusion: Baseline data reveal MRI detects CAA-related abnormalities presymptomatically, with increased burden over time