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[MUSIC PLAYING] ANDREW PAGE: Cancer surgery is a very broad subject

You will self-inject at home and come in for visits every few weeks so we can review progress and side effects

Side effects Common side effects of levothyroxine include headache, fatigue, weight changes, and changes in appetite

Lipotropic compounds improve fat oxidation, but without a muscle preservation stimulus, you'll lose lean mass alongside fat, which lowers metabolic rate and makes long-term maintenance harder

For metabolic studies where steady-state NAD+ elevation or weight change is the endpoint, switching routes after steady state is achieved (day 5+) has minimal impact on final outcomes, but document the change and consider it during analysis.

The investigator will assess the potential relationship between each AE and the study intervention