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HDL (High-Density Lipoprotein) helps clear cholesterol from the bloodstream, often dubbed good cholesterol. While HDL plays a protective role, the restespecially LDL, VLDL, IDL, lipoprotein(a), and remnantscan infiltrate artery walls, trigger inflammation, and promote plaque formation

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These results are consistent with the reported finding that cAMP stimulated the phosphorylation of CREB through PKA pathway [36, 38]