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We urgently need to develop new therapies with safe long-term toxicity profiles for rapid testing in clinical trials

In the CNS, both neurons and glial cells express cGAS and STING, and their activation by mtDNA has been directly implicated in neuroinflammation and NDDs [12, 93]

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The following day, after three washes with phosphate buffered saline with tween 20 (PBST), the plate was blocked for 2 hours at 37 C in PBS containing 5% skim milk