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The second bottleneck is the crew : even with a good supply line, repair cells (fibroblasts, and others) have to physically migrate into the wound and rebuild the matrix

Neuroscience 2014;281:68-76

doi: 10.1038/s44319-024-00278-4 78 ChenSJiangYZhengJLiPLiuMZhuYet al

NPJ Biofilms Microbiomes 143 ThomsenR

A lack of ferritin leads to an increase in the intracellular free iron concentration and ROS accumulation, making cardiomyocytes more susceptible to ferroptosis 26