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Similar to the systemic calcium signal transmission upon GSH treatment, Glu-induced [Ca 2+ ] cyt propagation in systemic leaves were strongly inhibited in GCaMP3/glr3.3 while remained unaffected in GCaMP3/glr3.6 (Supplementary Fig

The Trx system itself is a central hub of redox regulation, with its own redox status influencing numerous cellular processes beyond antioxidant defense

In addition to the CHOP signaling pathway, eIF2, a direct substrate of the PERK pathway, has also been implicated in immune responses in IBD (93)

Zhang F, Li ZL, Xu XM, Hu Y, Yao JH, Xu W, Jing HR, Wang S, Ning SL, Tian XF (2015) Protective effects of icariin-mediated SIRT1/FOXO3 signaling pathway on intestinal ischemia/reperfusion-induced acute lung injury