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Glycogen synthase kinase-3 beta (GSK3) phosphorylates PHGDH at its degron motif (T497/S501)

More fat is used as energy faster fat loss

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In the context of high levels of propionyl-CoA, citrate synthase produces methyl citrate, a dead end metabolite, from propionyl-CoA

It is possible to overload on certain vitamins, which can cause a range of symptoms depending on the vitamin

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