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Vitamin B12 injections may be administered weekly for 4 weeks, monthly or as needed

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furthermore, the S2-only vaccine was shown to induce nAb to both - and - coronaviruses (presumably to the fusion peptide as has been described in humans [69]), and it boosted a more broadly targeting antibody response overall than repeated homologous full-length spike vaccines [73]

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Mol Psychiatry 28:217229