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Nead KT, Sharp SJ, Thompson DJ, Painter JN, Savage DB, Semple RK, et al

Oxysterols from free radical chain oxidation of 7-dehydrocholesterol: product and mechanistic studies

therefore, viral hijack of this proprotein convertase enzyme could alter lipid metabolism, and affect blood pressure regulation and vascular remodeling in COVID-19 patients 344,345

demonstrated that age-related somatic mtDNA mutations could lead to defects in OXPHOS function, alter metabolic patterns, and accelerate the development of intestinal cancer