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20 These cells may be transplanted either in an undifferentiated state, following an in vitro preconditioning and/or predifferentiation using diverse biological stimuli ( e.g ., growth factors, biomaterials, signaling molecules, IVD-like nutrition conditions) or modified to overexpress specific markers to achieve a discogenic phenotype before implantation

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doi: 10.1159/000098399 231 IshiokaSEzakaYUmemuraKHayashiTEndoTSaitoT

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