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Interestingly, this mechanism has recently been linked to ferroptosis, the nonapoptotic form of cell death long implicated as a driver of T cell death in the TME in both humans and mice

Townsend DM

10.1038/s41580-020-00324-8 63 JiaoH.YangH.YanZ.ChenJ.XuM.JiangY.et al (2021)

The renal sources of ROS are leucocytes, fibroblasts, glomerular cells, interstitial cells, vascular cells, and activated macrophages

Recent reports indicate that ROS produced during liver transplantation were transferred to neighboring cells through Cx32 channels, aggravating oxidative stress and inflammation (Huang et al

Baicalin has been found to inhibit the growth of oxidative stress cells by inducing the ubiquitin-mediated degradation of NRF2, thereby affecting its stability