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Neuron 18, 9951008

Nabavinia MS, Yari A, Ghasemi-Esmailabad S, Gholoobi A, Gholizadeh L, Nabi A, et al

CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease

The MRSD can be further refined based on the anticipated therapeutic window : the dosage range sitting between the minimum effective concentration (MEC) and the minimum toxic concentration (MTC)

Lets take a step back

In the CY 2026 OPPS/ASC proposed rule (90 FR 33775), we proposed to align with the case threshold exemption from the Medicare Promoting Interoperability Program (77 FR 54080), the Hospital IQR Program (79 FR 50324), and the Hospital OQR Program (86 FR 63869)