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A.SciarrettaS.et al (2016)

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The neurosurgery care team at Cleveland Clinic helps find solutions for your brain, spine and nerves whether that means surgery or not.

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doi: 10.1080/15548627.2015.1053680 67 ZhangJPavlovaNNThompsonCB

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Several mutations in NPC1 cause the loss of lipid transporting ability, but the most frequent mutation, I1061T, leads to the disease due to its proteolysis at both the ER and the lysosomes (3, 4)

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