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Tumor-derived lactate suppresses cytotoxic T cell activity through multiple mechanisms: inhibiting T cell proliferation, reducing cytokine production, and promoting regulatory T cell (Treg) expansion

10.1016/j.intimp.2020.107179 69 LiX.JiangX

Like the mitochondria, the GSH/GSSG redox state of the nucleus (280 mV) is also more reduced than the cytoplasm (113, 127, 155, 338)

Establishing the factors impacting the gastrointestinal fate and toxicity of organic and inorganic food-grade nanoparticles

The mechanisms of other multidrug transporters, including P-glycoprotein (P-gp, ABCB1), ABCG2, and MRP1 have been well-studied

Arch Toxicol (2020) 94:144360