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Unlike conventional therapeutics, NADs induce long-lasting or curative effects due to their distinct physicochemical and biological properties

For example, sulforaphane attenuated cell necrosis and apoptosis in renal injury rats 51 and type 1 diabetes mice 52 models

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These carriers are further conjugated with brain-targeting agents such as lactoferrin and transferrin

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They also recommended expanding genotyping panels to include other relevant pharmacokinetic and pharmacodynamic genes beyond CYP2D6 and CYP2C19 , thereby capturing the full scope of genetic determinants influencing antidepressant response