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The pathway enrichment and pathway network topology analysis revealed that 14 metabolic pathways related to glaucoma, including glycine and serine metabolism, alanine metabolism, galactose metabolism, methionine metabolism, glutathione metabolism, purine metabolism, glutamate metabolism, urea cycle, spermidine and spermine biosynthesis, biotin metabolism, ammonia recycling, fructose and mannose deregulation, homocysteine deregulation and nucleotide sugar metabolism were significant (Figures 4A,B)

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Interestingly, some evidence suggests collagen supplementation in the setting of exercise recovery reduces joint pain and improves joint functionality but appears to have no significant effect on post-exercise muscle protein synthesis necessary for hypertrophy and muscle collagen protein synthesis