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Emerging research starts to point to a novel and compelling hypothesis that the sialoglycans posttranslationally appended to human ApoE may serve as a critical structural modifier that alters the biology of ApoE, leading to the opposing impacts of ApoE isoforms on sAD and likely in the peripheral systems as well

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Besides, histological examination revealed that animals pretreated with the extract displayed intact testicular morphology and spermatogenesis, with minor alterations in some tubules

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