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Biophysical basis for airway hyperresponsiveness

10.1038/onc.2012.334 41 DonzelliS.FontemaggiG.FaziF.Di AgostinoS.PadulaF.BiagioniF.et al

4 Oxidative stress and AD The pathophysiology of AD is multifaceted, and impaired aortic integrity is a fundamental mechanism in the pathology of AD, which results from the inherent instability of the aortic wall (e.g., due to inherited connective tissue diseases) or acquired conditions (e.g., atherosclerotic degeneration associated with aging) (64)

The IDO1-Kyn-AhR axis facilitates AhR nuclear translocation, which transcriptionally represses FTO, leading to m6A hypermethylation and stabilization of SLC7A11 transcripts

Infectious microorganisms, including Gram-negative and Gram-positive bacteria and certain fungi, can cause UTIs via the hematogenous route and ascending routes (26)

This means vegetarians and vegans may be at risk of having low levels of B12