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This was achieved using compounds targeting the mitochondrial ribosome, each inducing distinct stress response signatures

Successful PCR amplification with inverted primer PCR and failure of amplification with single primer PCR on all the samples of Alw-R (n = 20) indicates that the entire Alw-R colony has gene duplication in the same orientation (direct tandem duplication)

(PubMed) Desmoulin SK, Wang L, Polin L, et al

The dysregulation of the RAS system has been linked to a series of pathological conditions due to its effect on the function of mitochondria [133]

Fabricant, C