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When stress becomes chronic, the hypothalamicpituitaryadrenal (HPA) axis becomes dysregulated

Primary antibodies used in immunoblotting included polyclonal anti-AAGAB antibodies (Bethyl Laboratories, #A305-593A, RRID: AB_2782752), monoclonal antiAP2- antibodies (BD Biosciences, #610502, RRID: AB_397868), polyclonal antiAP2- antibodies (Bethyl Laboratories, #A304-719A, RRID: AB_2620914), monoclonal antiAP2- antibodies (BD Biosciences, #611350), and polyclonal antiAP2- antibodies (Abcam, #ab128950, RRID: AB_11140842)

doi: 10.1038/s41419-023-05716-0 73 PianiDFontanaA

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Oxidative Stress & Free Radicals: The Cellular Aging Culprits Every day, our cells are exposed to factors that produce free radicals pollution, poor diet, and even normal metabolic processes create these unstable molecules