bacterial and host-derived glutathione are required to activate prfa Frontiers Allosteric GSH binding primes PrfA

Allosteric GSH binding primes PrfA for DNA binding. (A and B) Download Scientific Diagram Structural basis of promiscuous inhibition of Listeria virulence activator PrfA by oligopeptides: Cell Reports Listeria monocytogenes utilizes glutathione and limited inorganic sulfur compounds as sources of essential cysteine Infection and Immunity The Role of the Glutathione System in Stress Adaptation, Morphogenesis and Virulence of Pathogenic Fungi Listeria monocytogenes requires phosphotransferase systems to facilitate intracellular growth and virulence PLOS Pathogens Streptococcus pyogenes Hijacks Host Glutathione for Growth and Innate Immune Evasion mBio

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