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doi:10.1016/0003-2697(77)90393-1

More than 90% of men over age 80 have the condition

This requires further exploration

Since physostigmine is rapidly destroyed, the patient may again lapse into coma after one to two hours, and repeated doses may be required

Even so, nursing mothers ingesting fava beans and the use of mothballs have been reported to trigger acute hemolytic anemia with jaundice in the neonatal period