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Our approach in Lige CHU consists of simultaneously measuring in blood samples four different kinds of biomarkers: enzymatic and non-enzymatic antioxidants, trace elements, markers of oxidative damage to lipids, and identification of sources leading to increased reactive oxygen species (ROS) production

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[] Thus, PERM1 is a novel effector of SMYD1-mediated epigenetic regulation of cardiac metabolism, revealing a muscle-specific pathway in which H3K4me3 is integrated with the transcriptional control of mitochondrial function through ERR [Figure 1]

doi: 10.1016/j.resmic.2017.09.007 166