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for 45 weeks

Within 5 min, the maximum temperature in the PDA@Pt + Laser group reached 43 , while the highest temperature in the saline + Laser group was 39.3

Moreover, curcumin is testified to induce mitophagy by its mitochondria-targeting peculiarity, which triggers the overactivity of SDH and superabundant ROS generation [298]

Environmental exposures (cigarette/e-cigarette smoke, air pollutants) disrupt pulmonary immune homeostasis, exacerbating disease severity through amplified inflammatory responses (55)

In this sense, some studies suggest that the cytokine storm that is present, especially in more severe COVID-19 patients, may activate the indoleamine 2,3-dioxygenase 1 (IDO-1) enzyme and, consequently, culminate in a drastic reduction of tryptophan, increases in toxic metabolites of the kynurenine pathway, and depression (Bouas et al

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