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Concurrently, ammonia inhibits the catalytic function of P4HA1 by chelating iron and competing with 2-oxoglutarate (2OG), thereby accelerating T cell exhaustion (173175)

In symptomatic B12 deficiency due to B12 malabsorption, parenteral administration of B12 is the default therapy

Lung Radiation-induced lung injury (RILI) is a prevalent and potentially fatal off-target effect of thoracic radiotherapy, with limited effective interventions available [56, 69, 70]

Exp Mol Med (2018) 50(1):e433

Se utiliza en el tratamiento y la prevencin de deficiencia de vitamina B12 en pacientes con condiciones como:_ Anemia addisoniana (perniciosa) Malabsorcin Gastritis atrfica Tratamiento prolongado con metformina Sobrecrecimiento bacteriano en el intestino delgado (SIBO) Gastrectoma total o parcial Infeccin con el parsito de los peces Diphyllobothrium latum Infeccin por Helicobacter pylori Disfuncin pancretica Malignidad pancretica o intestinal Deficiencia diettica (por ej

A human breast adenocarcinoma with chromosome and isoenzyme markers similar to those of the HeLa line