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SKU: 57147171905
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F.AltschulerR

For example, the lactylation of p53 at K120/139 impairs p53 LLPS, DNA binding, and transcriptional activation, contributing to tumorigenesis

Anti-inflammatory effects often manifest first, typically within 1 to 3 days

Targeting the p53-FOXO4 Axis: In senescent cells, the protein FOXO4 binds to p53 and sequesters it in the nucleus, preventing p53 from triggering cell death