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Clinical Trials: Impact of B12 Supplementation on Metabolites Below are four graphs showing the response to B12 supplementation of serum B12, holotranscobalamin, MMA, and homocysteine: Eight trials of predominantly older adults with at least mild deficiency (Dangour, 2015

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Un taux bas de vitamine B12 a rcemment t associ des cas de migraine chronique, et une homocystine leve, accompagne de cofacteurs dficients et danomalies du gne MTHFR (qui permet le passage de THF M-THF), a t lie la migraine avec aura, cause dune synthse dfaillante de mthionine, menant une accumulation dhomocystine, elle-mme gnratrice despces ractives de loxygne (causant un stress oxydatif)

Weve talked about both cyanocobalamin and methylcobalamin but there are other forms of B12 that you should know about