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The Chemistry of Endogenous and Exogenous Reactive Oxygen Species Formation As previously observed, free radicals composed of oxygen are mainly formed by an electron transfer reaction through several pathways, with the main group of ROS being formed during natural biological processes in aerobic cells

The hepatic GSH is inversely related to hepatic MGO and positively correlates with the hepatic GLO activity whereas the hepatic GLO activity is positively correlated with the hepatic d-lactate [76]

Cell Metab 15: 110121 Letouze E, Martinelli C, Loriot C, Burnichon N, Abermil N, Ottolenghi C, Janin M, Menara M, Nguyen AT, Benit P, Buffet A, Marcaillou C, Bertherat J, Amar L, Rustin P, De Reynies A, GimenezRoqueplo AP, Favier J (2013) SDH mutations establish a hypermethylator phenotype in paraganglioma