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Description

This system enables the simultaneous measurement of oxygen consumption rate (OCR), reflecting mitochondrial oxidative phosphorylation, and extracellular acidification rate (ECAR), indicative of glycolytic activity

Roos D, de Boer M (2014) Molecular diagnosis of chronic granulomatous disease

In some structures of activated-IdeR, the third metal (cobalt)-binding site located on the surface of Domain 3 was also observed, and this metal is coordinated by His219, His223, and four water molecules