glutathione s-transferase gst activity Erythrocyte transferase: a general probe for chemical contaminations in mammals Glutathione S-transferase (GST) specific activity

Oxidative stress, molecular inflammation and sarcopenia

Studies have demonstrated that ethanol-induced liver injury is related to excessive generation of free radicals and consequently oxidative stress (Morel and Barouki, 1999

10.1016/0163-7258(89)90050-8 161 RamachandranP

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In cancer cell lines, the mTORC1 signal can also promote de novo lipid synthesis through the sterol responsive element-binding protein (SREBP) transcription factors, which induce the expression of metabolic genes responsible for lipid biosynthesis, including fatty acid synthase (FASN) (Duvel et al., 2010)

Moreover, dysfunctional signaling via group I mGluRs is thought to lead to defective internalization of GluR2-containing AMPA receptors, which may also influence the permeability of the cellular membrane to Ca 2+ (Feng et al., 2+ influx