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After 72 weeks, average weight loss was 16.0% at 5mg, 21.4% at 10mg, and 22.5% at 15mg

Metalloproteinase regulation studies document MMP1 and MMP2 gene expression increases at 0.01 nM with TIMP1 increases at all tested concentrations (0.01-100 nM)

CHE treatment was found to exhibit excellent anticancer effects in prostate cancer cells by inducing ROS-dependent ER stress (Wu et al., 2018), which reduced Bcl-2 and increased cleaved PARP

Isoalantolactone induces reactive oxygen species mediated apoptosis in pancreatic carcinoma PANC-1 cells

Definition of leukemia-initiating cells by their growth in SCID mice

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