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The effect of pericardiectomy on maximal oxygen consumption and maximal cardiac output in untrained dogs

This aggravates oxidative stress and accelerates ferroptosis (170)

L-theanine also stabilizes glutamatergic concentrations in the brain, which may explain its therapeutic effect in patients with schizophrenia (21)

Acute or chronic

Despite the initial shift toward glycolysis, microglia in advanced stages of Alzheimer's disease experience a decline in both glycolytic and oxidative phosphorylation pathways, resulting in a state of energetic exhaustion that impairs their ability to clear debris and protect neurons (103)

Therefore, various strategies to improve their therapeutic efficiency (application of other anticancer effects of cyanine dyes, improvement in the tumor selectivity of cyanine dyes and their combination with other therapeutic agents and therapies) are intensively studied