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Walking distance tends to be the most profoundly affected

Neuroprotection by Zinc in Ischemia In contrast to chelation-based therapeutic intervention, various studies have demonstrated neuroprotective benefits following the administration of various zinc compounds

Fikru A, Makonnen E, Eguale T, Debella A, Mekonnen GA

When combined with insulin or sulfonylureas, dose adjustments of these medications are frequently necessary to reduce the risk of hypoglycemia, as the glucose-lowering effects may be additive

Furthermore, inhibiting the cGAS/STING pathway with RU.521 upregulates the expression of SLC7A11 and GPX4, which mitigates microglial ferroptosis (Sui et al., 2025)