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Platelet isolation and platelet functional studies Human blood was drawn from the antecubital vein and mixed with an ACD solution (85 mM sodium citrate, 71.38 mM citric acid and 27.78 mM glucose) in a 9:1 volume ratio

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Nasal samples offer accessibility but incompletely represent lower airway oxidative stress (Jeanson et al., 2014), whereas EBC presents biomarker potential despite standardization challenges (Causer et al., 2020

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