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Such functional cobalamin deficiency may arise when there is increased binding of vitamin B 12 to haptocorrin as opposed to transcobalamin II, with subsequent reduction in delivery of the vitamin to peripheral cells

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*Correspondence: Jiang-Hua Li, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

If the deficiency is severe, remarkably, it can lead to permanent nerve damage

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