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J Cataract Refract Surg 35:214953, PMID: 19969222 Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA (2009) Nitric oxide in cell survival: a Janus molecule

The cell-type-specific loss of Fmr1 in PV-expressing neurons led to anxiety-like behavior, impaired social behavior, and dysregulated de novo protein synthesis

Steady state studies varying NADPH and inhibitor concentrations indicate that treatment with the fast inhibitors 7 and 8 or the slow inhibitor 3 , (the only slow inhibitor reaching equilibrium in 6 h), resulted in decreases in both K m and V max values consistent with uncompetitive inhibition of TGR, while treatment with 9 , a close analog of compound 8 synthesized ad hoc to facilitate structural studies (see below), changed only the V max indicating noncompetitive inhibition (Supplementary Tables 15 and 16)

Researchers choosing between the two should base their selection on which receptor targets are relevant to their specific experimental design

Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL 33 mcg on a U-100 insulin syringe

doi: 10.1016/j.jep.2015.11.021 126 XingWSongYLiHWangZWuYLiCet al