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All authors contributed to the study conception and design

Colon rectal cancer is considered one of the cancers most directly associated with dietary habits, especially high consumption of protein and low intake of fibers (206)

SIRT2 Mediates NADH-Induced Increases in Nrf2, GCL, and Glutathione by Modulating Akt Phosphorylation in PC12 Cells

Proteoliposome counterflow assays Frozen proteoliposome and protein-free liposome aliquots (lipid concentration: 8 mg/ml) were thawed and diluted twofold in internal liposome buffer with final concentrations of 150mM KCl, 50mM HEPES (pH 7.4), 5 mM (Figure 3a and Extended Data Figure 4l) or 10 mM (Extended Data Figure 7F) unlabeled GSSG (Thermo J63715.06)

Aging Cell 4 , 119125 (2005)

Those with chronic liver or kidney disease need medical oversight before using glutathione, as their bodies may process it differently