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For example, free quercetin displays structural instability under light or oxidative stress, resulting in a substantial decline in both antioxidant and anti-inflammatory activities, potentially rendering it therapeutically ineffective (Vale et al., 2021)

[14] In vitro and clinical pharmacology data further demonstrate potentiation of xerostomia, hyperthermia, and tachyarrhythmia when combined with other anticholinergic agents such as tricyclic antidepressants or phenothiazines

2024 Jun 17;134(12):e179742

All primers used for pyrosequencing are listed in Supplementary Table 6

Amyloid precursor proteins are protective in Drosophila models of progressive neurodegeneration

Tumor-activated carrier-free prodrug nanoparticles for targeted cancer immunotherapy: preclinical evidence for safe and effective drug delivery