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Acetyl L-Carnitine therefore has a more specific action on brain function than L-Carnitine , and may be useful for supporting memory and concentration, improving cognitive function and combating brain aging

Safety Considerations Common Mild Side Effects Nausea and stomach discomfort Diarrhea Fishy smell in breath or sweat (rare) Who Should Consult a Doctor First Individuals with heart diseases People with kidney problems Those with hormonal disorders Pregnant and nursing women Research Consideration: TMAO Some studies raise concerns about high levels of L-Carnitine from supplements possibly leading to increased TMAO (trimethylamine-N-oxide) production, which has been associated with higher risk of heart diseases

6 Pistone G, Marino AD, Leotta C, et al

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Of course, this may need to be adapted to individual patients (e.g., alcohol-withdrawal seizures respond best to phenobarbital)

9ce) increased DNA-damage foci in CCNE1 -overexpressing cells but not in control cells (Fig