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It plays an important role in the synthesis and oxidation of fatty acids, pyruvate oxidation in the citric acid cycle, and other biological processes

Available online at: (Accessed October 16, 2023)

The pentose phosphate pathway (PPP) is the major supply of NADPH in cells and so cells were incubated with 6-amino nicotinamide, a known inhibitor of the PPP enzyme 6-phosphogluconate dehydrogenase

However, risks include surgical complications, hemorrhage, infection, and neuropsychiatric side effects, necessitating careful patient selection and multidisciplinary evaluation (Cury et al., 2022

88 In recent years, studies have revealed that UA activates the TLR4-NLRP3 inflammatory complex, which is a multi-protein complex that plays a pivotal role in initiating the innate immune response to various danger signals, including MSU crystals

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